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5-MeO-DMT freebase
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5-MeO-DMT Freebase
5-MeO-DMT (5-Methoxy-N,N-dimethyltryptamine) is a powerful naturally occurring tryptamine known for its potent psychoactive effects. Offered in its freebase form for ease of handling and precise dosing in research settings. Primarily used for studying serotonergic activity and its effects on the central nervous system. For laboratory research use only. Not for human consumption.
🧪 Buy 5-MeO-DMT Freebase Online – Advanced Tryptamine Reference Material for Research Applications
🔬 Overview
5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a naturally occurring tryptamine compound and an important molecule in analytical, forensic, and biochemical research.
Its presence has been documented in several plant and animal species, and in recent decades, it has become a benchmark reference compound for laboratories studying the tryptamine class of indole alkaloids.
In its freebase form, 5-MeO-DMT appears as a crystalline, volatile solid, ideal for use in analytical method development and forensic comparison studies.
Global Chems Depot provides high-purity analytical-grade 5-MeO-DMT Freebase, intended solely for research and educational purposes — not for human or veterinary use.
⚗️ Chemical Background of analytical tryptamine compound
5-MeO-DMT is structurally related to DMT (N,N-dimethyltryptamine) and bufotenine (5-HO-DMT), forming part of a core group of indole-based alkaloids.
Its methoxy substitution at the 5-position of the indole ring alters its electronic and metabolic properties, making it an excellent candidate for comparative research into structure–activity relationships (SAR) and enzyme interaction mechanisms.
Because of its biological relevance and detectability in forensic samples, 5-MeO-DMT is one of the most widely studied tryptamines within modern analytical chemistry.
⚛️ Physical and 5-MeO-DMT analytical data
| Property | Detail |
|---|---|
| Chemical Name | 5-Methoxy-N,N-dimethyltryptamine |
| Molecular Formula | C₁₃H₁₈N₂O |
| Molecular Weight | 218.30 g/mol |
| Compound Class | Tryptamine / Indole Alkaloid |
| Form | Freebase (crystalline or waxy solid) |
| Purity | ≥ 99% analytical grade |
| CAS Number | 1019-45-0 |
| Appearance | Off-white to beige crystalline solid |
| Storage | Store below –20 °C, protected from light and air |
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DMT analogue forensic analysis Applications in Analytical Research
1. Analytical Method Validation
5-MeO-DMT serves as a primary standard for validating chromatographic and spectrometric techniques, including LC-MS/MS, GC-MS, and FT-IR.
Its clean fragmentation pattern and distinct retention time make it invaluable for instrument calibration and method verification when analyzing complex biological or botanical matrices.
2. Forensic Toxicology
In forensic laboratories, 5-MeO-DMT is used as a reference compound for the identification of tryptamine derivatives in seized materials and biological specimens.
Accurate spectral data allow analysts to differentiate 5-MeO-DMT from other psychoactive tryptamines such as DMT, DET, and 4-AcO-DMT.
3. Metabolic and Enzymatic Studies
Research into 5-MeO-DMT metabolism contributes to understanding monoamine oxidase (MAO) enzymatic pathways and indoleamine metabolism.
Academic laboratories utilize the compound to study oxidative deamination, O-demethylation, and metabolite profiling using modern analytical instrumentation.
4. Spectral Database Development
Reference spectra generated from high-purity 5-MeO-DMT samples are archived in forensic spectral databases (e.g., SWGDRUG, Cayman, and NIST libraries), enhancing data reliability and cross-laboratory reproducibility.
5. Educational and Comparative Research
In academic environments, 5-MeO-DMT Freebase is a cornerstone material for analytical chemistry education, allowing students and researchers to explore tryptamine structure elucidation, chromatographic separation, and spectral interpretation.
🌍 Relevance 5-MeO-DMT analytical data in Modern Research
As the landscape of new psychoactive substances (NPS) evolves, 5-MeO-DMT maintains significance as a reference molecule that bridges classical tryptamine chemistry with modern analytical methodologies.
Its inclusion in forensic libraries and toxicological datasets strengthens scientific monitoring of emerging indole derivatives.
Because of its naturally occurring status and unique molecular profile, 5-MeO-DMT continues to serve as a benchmark compound for identifying and classifying new analogues.
🧫 Analytical Characterization of high purity 5-MeO-DMT research chemical
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Mass Spectrometry (MS): Displays major ions at m/z 130, 159, and 218, with characteristic fragmentation consistent with N,N-dimethyltryptamines.
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Infrared (IR) Spectroscopy: Prominent peaks at ~2,800–2,950 cm⁻¹ (C–H stretch), 1,600 cm⁻¹ (aromatic C=C), and 1,220 cm⁻¹ (C–O–C stretch).
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UV-Vis Spectroscopy: Absorption maximum at ~278 nm, typical for indole chromophores.
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NMR (¹H and ¹³C): Reveals chemical shifts confirming the 5-methoxy substitution and dimethylaminoethyl chain.
These analytical signatures enable unambiguous identification and quantification in both qualitative and quantitative research.
⚖️ Legal and Regulatory Status of analytical tryptamine compound
5-MeO-DMT is controlled or restricted in several jurisdictions due to its structural similarity to other psychoactive tryptamines.
Researchers must ensure full compliance with national and regional regulations governing the possession, transport, and use of this compound.
All handling must occur within licensed laboratories under proper authorization, following chemical safety and documentation protocols.
🧠 Safety, Handling, and Storage Methods to Buy 5-MeO-DMT Freebase online
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Handle only in controlled laboratory settings using gloves, goggles, and standard PPE.
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Avoid exposure to heat, light, and moisture.
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Use appropriate fume extraction when weighing or transferring samples.
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Store securely in airtight amber glass vials at sub-zero temperatures.
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Dispose of residual material according to hazardous waste regulations.
Following these precautions preserves sample integrity and ensures compliance with laboratory safety standards.
🧬 Scientific Importance of 5-MeO-DMT analytical data
The study of 5-MeO-DMT contributes to several important scientific fields:
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Neurochemistry: Insight into serotonin receptor interactions and metabolic transformations.
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Forensic Toxicology: Development of detection protocols for tryptamine analogues.
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Analytical Chemistry: Expansion of spectral libraries and validation of chromatographic techniques.
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Comparative Botany: Identification of natural tryptamine sources in plant and animal species.
By serving as a standard reference compound, 5-MeO-DMT helps scientists refine methods for detecting and characterizing new psychoactive substances across disciplines.
📘 Summary of DMT analogue forensic analysis
| Compound Type: | Indole-based tryptamine |
| Form: | Freebase solid |
| Purity: | ≥ 99% analytical standard |
| CAS Number: | 1019-45-0 |
| Applications: | Forensic reference • Analytical validation • Comparative chemical studies |
| Research Use Only: | Not for human or animal consumption |
⚠️ Important Disclaimer
All information provided is intended solely for scientific, analytical, and educational purposes.
5-MeO-DMT Freebase is not for human or veterinary use and must be handled only by qualified personnel in licensed facilities.
Any unauthorized use may violate local or international regulations.
| QUANTITY | 2g, 5g |
|---|



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