βOH-2C-B hydrochloride

Buy βOH-2C-B Online– High-Purity β-Hydroxy-2C-B Research Chemical | ≥98% Lab-Tested (2026)

βOH-2C-B hydrochloride (β-Hydroxy-2,5-dimethoxy-4-bromophenethylamine hydrochloride), commonly abbreviated as βOH-2C-B research chemical, βOH-2C-B powder, or βOH-2C-B HCl, is a synthetic ring-substituted phenethylamine and hydroxylated metabolite/analog of the classic psychedelic 2C-B (2,5-dimethoxy-4-bromophenethylamine). The β-hydroxy group at the ethylamine side chain creates a compound with potentially altered pharmacokinetics, metabolic stability, receptor affinity, and duration compared to the parent 2C-B or other 2C-X analogs (2C-I, 2C-E, 2C-C, 2C-T-7, 2C-P).

Since its first mentions in research literature and analytical detections around 2018–2020, βOH-2C-B hydrochloride has gained traction as a valuable probe in psychedelic pharmacology, 5-HT2A receptor selectivity studies, structure-activity relationship (SAR) investigations, forensic toxicology method development, and comparative phenethylamine metabolism research. As a hydroxylated derivative, βOH-2C-B research chemical serves as both a potential active metabolite of 2C-B and a standalone compound for studying hydroxy substitution effects in the 2C family.

Each batch of βOH-2C-B powder is supplied as a fine, white to off-white crystalline material with ≥98% purity, independently confirmed by third-party high-performance liquid chromatography (HPLC), liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS), gas chromatography-mass spectrometry (GC-MS), and proton nuclear magnetic resonance (¹H-NMR). The product is vacuum-sealed in tamper-evident, moisture-resistant foil pouches or amber glass vials, accompanied by a current batch-specific Certificate of Analysis (COA), lot traceability, and explicit “Research Use Only – Not for Human Consumption” labeling.

βOH-2C-B for sale is offered exclusively for legitimate scientific research, analytical reference standard preparation, forensic method development/validation, toxicological profiling, 5-HT2A receptor binding studies, behavioral pharmacology, and educational purposes. It is not intended, labeled, or sold for human or veterinary consumption, diagnostic use, therapeutic application, or any form of in-vivo experimentation outside approved research protocols.

Chemical & Physical Specifications – βOH-2C-B Hydrochloride Research Chemical

• Chemical Name: 2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanol hydrochloride (β-hydroxy form)
• IUPAC Name: 2-(4-Bromo-2,5-dimethoxyphenyl)-2-hydroxyethanamine hydrochloride
• Synonyms: βOH-2C-B, β-Hydroxy-2C-B, 2C-B β-hydroxymetabolite, BOH-2C-B HCl
• CAS Registry Number: Not yet assigned (emerging research compound)
• Molecular Formula: C₁₀H₁₄BrNO₃ • HCl
• Molecular Weight: 312.59 g/mol (hydrochloride salt)
• Appearance: White to off-white fine crystalline powder
• Purity: ≥98.0% (third-party verified by HPLC, LC-QTOF-MS, GC-MS, ¹H-NMR)
• Form: Vacuum-sealed, tamper-evident packaging
• Solubility: Highly soluble in water, ethanol, methanol, DMSO; moderately soluble in chloroform
• Storage Conditions: Cool (2–8 °C), dry, dark, airtight container – protect from light, heat, humidity & air exposure
• Shelf Life: Typically 24–36 months under recommended conditions

Primary Research Applications of βOH-2C-B research chemical (2026 Trends)

βOH-2C-B hydrochloride research chemical has established itself as a valuable probe in psychedelic pharmacology, analytical chemistry, and forensic toxicology laboratories due to its position as a potential primary metabolite of 2C-B and its unique hydroxy-substituted phenethylamine structure.

Key active research areas in 2026 include:

• 5-HT2A Receptor Agonism & Functional Selectivity As the β-hydroxy metabolite of 2C-B, βOH-2C-B exhibits potent partial agonism at 5-HT2A receptors. It is used to investigate biased agonism, β-arrestin recruitment, head-twitch response (HTR) in mice, and potential therapeutic windows versus classic hallucinogenic intensity.
• Comparative Pharmacokinetics & Metabolism Researchers compare oral bioavailability, half-life, and metabolite ratios of βOH-2C-B hydrochloride versus 2C-B, 2C-B-FLY, 25B-NBOMe, and other 2C-X compounds. The β-hydroxy group offers insights into phase I hydroxylation pathways and potential active metabolite contributions to parent compound effects.
• Structure-Activity Relationship (SAR) Studies The combination of 2,5-dimethoxy substitution, 4-bromo halogen, and β-hydroxy side chain allows systematic exploration of how hydroxy modification influences potency, duration, receptor selectivity, and subjective effect profiles in animal models.
• Metabolite Identification & Forensic ToxicologyβOH-2C-B and its conjugated forms (glucuronide, sulfate) are major metabolites of 2C-B detected in urine, blood, hair, and oral fluid. High-purity βOH-2C-B powder is essential for synthesizing reference standards, validating LC-QTOF-MS and GC-MS/MS methods, and confirming identity in routine NPS/phenethylamine screening panels.
• Behavioral Pharmacology & Animal Models Rodent head-twitch response (HTR), wet-dog shakes, locomotor activity, drug discrimination, and electrophysiological studies frequently use βOH-2C-B dosage ranges of 0.3–10 mg/kg i.p. or s.c. to evaluate psychedelic-like activity and cross-tolerance with 2C-B, DOB, DOM, and LSD.
• Analytical Method Development & ValidationβOH-2C-B is routinely included in expanded phenethylamine/NPS screening panels because it elutes close to 2C-B, 2C-I, 2C-E, and other 2C-X, requiring careful chromatographic separation and mass-spectral differentiation. It is also used to challenge the specificity of immunoassays and designer-drug screening tests.

Typical Research Dosage Ranges (Reference Only – 2026)

βOH-2C-B dosage varies significantly depending on the experimental model:

• Analytical calibration & reference standard preparation: 0.05–5 mg (standard curves, quality control)
• In-vitro receptor binding / functional assays (5-HT2A): 0.1 nM – 10 μM (most active window: 10–300 nM)
• Rodent head-twitch response & behavioral pharmacology: 0.3–10 mg/kg i.p. or s.c. (dose-response curves common)
• High-dose neurochemical or toxicity modeling: 10–30 mg/kg (ethically restricted, IACUC-approved only)

Most published βOH-2C-B research centers on the 1–10 mg/kg range in vivo and 10 nM – 300 nM concentrations in cellular/receptor assays.

Safety, Handling & Regulatory Notes – buy βOH-2C-B online

βOH-2C-B research chemical is a potent serotonergic psychedelic metabolite and should be handled only under controlled laboratory conditions:

• Work exclusively in a certified Class II biological safety cabinet or fume hood
• Wear appropriate PPE: nitrile gloves, lab coat, safety goggles, and respiratory protection
• Prevent skin contact, inhalation, and aerosol generation
• Dispose of all waste as hazardous chemical material per institutional and local regulations
• Store in amber glass vials, sealed, at 2–8 °C, protected from light, heat, humidity, and air exposure

βOH-2C-B side effects in research models are primarily related to serotonergic overstimulation: head-twitch response, wet-dog shakes, hyperthermia, tachycardia, and potential serotonin syndrome-like symptoms at high doses.

Legal status 2026: βOH-2C-B is controlled or monitored in many jurisdictions under analogue acts, temporary class drug orders, or specific NPS legislation. It is sold exclusively for legitimate scientific research, analytical reference, forensic calibration, and educational purposes. Buyers must independently confirm βOH-2C-B legal status in their jurisdiction prior to ordering.

Why Laboratories Consistently Choose Our βOH-2C-B Hydrochloride Powder

• Third-party HPLC, GC-MS & NMR verified purity ≥98% – batch-specific COA included with every shipment
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, and method validation
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing risk
• Superior handling properties – fine, non-static powder with excellent flowability and solubility in common research solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, and research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance audits

We understand the critical role high-purity reference materials play in psychedelic pharmacology, forensic toxicology, and analytical chemistry — every βOH-2C-B order is backed by that commitment.

Conclusion: Advance Phenethylamine & Psychedelic Metabolite Research with High-Purity βOH-2C-B Hydrochloride

In 2026, βOH-2C-B hydrochloride (β-Hydroxy-2C-B) remains a valuable and increasingly studied metabolite in laboratories exploring 5-HT2A receptor agonism, 2C-X metabolism, novel NPS emergence, and comparative SAR within the ring-substituted phenethylamine family. Its high purity, consistent quality, reliable supply, and precise handling characteristics make βOH-2C-B hydrochloride powder an indispensable tool for rigorous psychedelic, neuropharmacological, analytical, and forensic research.

Order your laboratory-grade βOH-2C-B hydrochloride today – strictly for scientific research, analytical, and forensic applications. Fast, discreet, tracked global delivery with full documentation and batch traceability.