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2-METHYL-AP-237 20mg Pellets
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2-Methyl-AP-237 20mg Pellets – High-Purity Research Chemical
2-Methyl-AP-237 20mg Pellets are precisely dosed, high-purity synthetic opioids designed for scientific research. Each pellet contains 20 milligrams of 2-Methyl-AP-237, a potent opioid analgesic structurally related to AP-237 (bucinnazine). This compound has been associated with significant analgesic effects and rapid onset of action, similar to fentanyl, and has been linked to serious adverse events, including fatalities. Due to its potency, it is classified as a Schedule I substance under the 1961 Single Convention on Narcotic Drugs and is subject to international control.
buy 2-Methyl-AP-237 research compound: Chemical Structure, Analytical Profile & Research Overview
🧪 Introduction
2-Methyl-AP-237 (2-methyl-2’-[(dimethylamino)methyl]-4’-hydroxy-4-phenylmorphinan) is a synthetic morphinan-class compound studied within the context of analytical chemistry, structural biology, and chemical reference research.
Belonging to the morphinan family, 2-Methyl-AP-237 draws scientific interest because of its methyl substitution at the 2-position, which subtly changes its molecular conformation, receptor interaction potential, and physicochemical stability.
Researchers in forensic and analytical sciences study 2-Methyl-AP-237 to understand structure–activity relationships (SAR), chromatographic behavior, and spectroscopic characteristics.
⚠️ Disclaimer: This information is for academic and scientific purposes only. 2-Methyl-AP-237 is not approved for human or veterinary use.
⚗️ Chemical Structure and high purity 2-Methyl-AP-237 properties
Property | Detail |
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IUPAC Name | 2-Methyl-2’-[(dimethylamino)methyl]-4’-hydroxy-4-phenylmorphinan |
Molecular Formula | C18H25NO2 |
Molecular Weight | 287.4 g/mol |
Chemical Class | Morphinan / Synthetic Analogue |
Functional Group | 2-methyl substitution on the morphinan backbone |
The morphinan structure consists of a multi-ring system with a nitrogen atom contributing to basicity and receptor activity potential.
The addition of a methyl group in the 2-position introduces steric hindrance, influencing both binding dynamics and molecular orientation, making it a valuable candidate for computational modeling and spectroscopic calibration.
🔬 Research and Analytical Applications Of synthetic morphinan chemistry
1. Analytical Reference Standard
In forensic and toxicological laboratories, 2-Methyl-AP-237 is utilized as an analytical reference material to develop, validate, and calibrate chromatographic and mass spectrometric methods.
It assists in identifying structurally related morphinans and distinguishing them in complex sample matrices.
2. Spectroscopic Characterization
Analytical chemists use NMR, IR, and UV–Vis spectroscopy to identify the compound’s structural fingerprints.
These data contribute to the creation of spectral libraries, essential for rapid and accurate compound identification.
3. Structure–Activity Relationship (SAR) Studies
Through molecular comparison with related compounds like AP-237 and AP-238, 2-Methyl-AP-237 helps clarify how small structural modifications — such as alkyl or hydroxyl substitutions — impact binding affinity, solubility, and metabolic behavior.
4. Metabolic and Stability Analysis
Controlled laboratory testing explores how 2-Methyl-AP-237 behaves under oxidative and hydrolytic conditions, offering insights into degradation pathways and chemical resilience.
⚛️ Analytical Techniques of 2-Methyl-AP-237 chemical structure
Technique | Purpose in Research |
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Gas Chromatography–Mass Spectrometry (GC–MS) | Compound identification and fragmentation pattern study |
High-Performance Liquid Chromatography (HPLC) | Purity verification and retention time analysis |
Nuclear Magnetic Resonance (NMR) | Confirmation of molecular framework and substitution pattern |
Fourier-Transform Infrared Spectroscopy (FT-IR) | Identification of characteristic amine and hydroxyl bands |
Ultraviolet–Visible (UV–Vis) Spectroscopy | Optical stability and absorbance characterization |
These techniques ensure high analytical reproducibility, helping researchers maintain data integrity across different laboratory environments.
🧠 Scientific Significance and Context of 2-Methyl-AP-237 analysis
The morphinan class includes several structurally rich compounds that serve as reference models for receptor-binding research, analytical detection, and stereochemical evaluation.
2-Methyl-AP-237’s chemical profile allows scientists to:
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Investigate molecular stability under various conditions
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Analyze hydrophobic vs. hydrophilic interactions
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Simulate molecular docking for receptor-ligand modeling
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Refine chromatographic separation for morphinan analogs
Its ability to remain stable across pH and temperature gradients makes it particularly useful in long-term analytical calibration studies.
Additionally, computational chemistry simulations using 2-Methyl-AP-237 can explore conformational changes and steric effects within the morphinan nucleus, enriching our understanding of molecular adaptability in this compound class.
🧫 Laboratory Handling and Safety
All analytical handling should take place in authorized research facilities under the supervision of qualified chemists.
Best laboratory practices include:
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Conducting research in ventilated fume hoods
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Wearing appropriate PPE (gloves, goggles, lab coats)
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Avoiding direct skin or respiratory exposure
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Labeling samples clearly and storing them in sealed containers
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Keeping materials away from direct sunlight and high humidity
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Disposing of residues according to institutional waste management policies
⚠️ This compound is intended solely for laboratory analytical use and must never be used for in vivo or non-scientific applications.
⚖️ Legal and Regulatory Overview to buy 2-Methyl-AP-237 research compound
The legal status of 2-Methyl-AP-237 can differ internationally. While it may not be scheduled in all regions, analog laws and psychoactive substance regulations may still apply.
To ensure compliance:
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Check current national and local regulations before import, storage, or use
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Maintain full traceability and documentation of laboratory activities
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Limit access to trained research personnel only
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Follow institutional chemical registration and record-keeping policies
Transparency and proper documentation strengthen both scientific credibility and regulatory security for any ongoing research.
🌐 Research Fields Related to synthetic morphinan chemistry
2-Methyl-AP-237 plays a supporting role in several academic and technical domains, including:
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Forensic Toxicology: for comparative detection methods
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Computational Chemistry: for energy-state modeling of substituted morphinans
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Analytical Science: for spectral reference calibration
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Synthetic Organic Chemistry: as a framework for studying morphinan synthesis pathways
These multidisciplinary applications demonstrate 2-Methyl-AP-237’s value as a reference and model compound for emerging morphinan research.
🧾 Conclusion
2-Methyl-AP-237 (20 mg Pellets) stands as a chemically significant morphinan derivative, essential for analytical, spectroscopic, and structural research.
Its precise molecular architecture and stability under varying conditions make it a reliable model for exploring morphinan chemistry, fluorine substitution, and analytical detection techniques.
Through the combined use of chromatographic, spectroscopic, and computational methods, scientists can derive deeper insights into how small atomic modifications affect molecular behavior within complex ring systems.
When handled responsibly within authorized facilities, 2-Methyl-AP-237 continues to enrich forensic, analytical, and structural chemistry — driving progress in the accurate identification and classification of novel compounds.
QUANTITY | 250g, 500g |
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