3-CEC

buy 3-CEC online – High-Purity 3-Chloroethcathinone Research Chemical | Lab-Tested (2026)

3-CEC (3-Chloroethcathinone), commonly referred to as 3-CEC research chemical, 3-CEC powder, 3-chloroethcathinone or meta-chloroethcathinone, is a synthetic substituted cathinone belonging to the β-keto amphetamine class. It features a chlorine atom at the meta (3) position of the phenyl ring, combined with the classic cathinone backbone (β-keto, N-ethyl substitution). This structural placement of the chlorine gives 3-CEC distinct physicochemical and pharmacological properties compared to its positional isomers (4-CEC, 2-CEC), the parent ethcathinone, and other halogenated cathinones such as 3-FMC, 4-CL-PVP, 3-CMC, and 4-CMC.

First reported in analytical and seized-drug literature around 2015–2017, 3-CEC has maintained steady relevance in forensic toxicology, analytical chemistry, neuropharmacology, and structure-activity relationship (SAR) studies due to periodic detections in polydrug samples, driving-under-the-influence cases, overdose reports, and expanded novel psychoactive substance (NPS) screening panels.

Every batch of 3-CEC powder is supplied as a fine, white to off-white crystalline material with ≥98% purity, independently confirmed by third-party high-performance liquid chromatography (HPLC), liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS), gas chromatography-mass spectrometry (GC-MS), and proton nuclear magnetic resonance (¹H-NMR). The product is vacuum-sealed in tamper-evident, moisture-resistant foil pouches or amber glass vials, accompanied by a current batch-specific Certificate of Analysis (COA), lot traceability, and explicit “Research Use Only – Not for Human Consumption” labeling.

3-CEC for sale is offered exclusively for legitimate scientific research, analytical reference standard preparation, forensic method development/validation, toxicological profiling, monoamine transporter assays, behavioral pharmacology, and educational purposes. It is not intended, labeled, or sold for human or veterinary consumption, diagnostic use, therapeutic application, or any form of in-vivo experimentation outside approved research protocols.

Chemical & Physical Specifications – 3-CEC Research Chemical

• Chemical Name: 1-(3-Chlorophenyl)-2-(ethylamino)propan-1-one
• IUPAC Name: 1-(3-Chlorophenyl)-2-(ethylamino)propan-1-one
• Synonyms: 3-CEC, 3-Chloroethcathinone, meta-Chloroethcathinone
• CAS Registry Number: 777666-01-2 (freebase)
• Molecular Formula: C₁₁H₁₄ClNO
• Molecular Weight: 211.69 g/mol (freebase)
• Appearance: White to off-white fine crystalline powder
• Purity: ≥98.0% (third-party verified by HPLC, LC-QTOF-MS, GC-MS, ¹H-NMR)
• Form: Vacuum-sealed, tamper-evident packaging
• Solubility: Highly soluble in ethanol, methanol, DMSO, chloroform; moderately soluble in acidified water
• Storage Conditions: Cool (2–8 °C), dry, dark, airtight container – protect from light, heat, humidity & air exposure
• Shelf Life: Typically 24–36 months under recommended conditions

Why Laboratories & Researchers Choose Our 3-CEC Powder

• Third-party HPLC, LC-QTOF-MS, GC-MS & NMR verified purity ≥98% – batch-specific COA included with every shipment
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, method validation, calibration curves, and inter-laboratory reproducibility
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing risk
• Superior handling properties – fine, low-static powder with excellent flowability and solubility in common analytical solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, government agencies & research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance audits

We understand the critical role high-purity reference materials play in analytical chemistry, forensic toxicology, and neuropharmacology — every 3-CEC order is backed by that commitment.

Primary Research Applications of 3-CEC (2026 Trends)

3-CEC research chemical remains one of the most persistently requested synthetic cathinones in forensic, toxicological, and pharmacological laboratories worldwide due to its continued detections in illicit markets, polydrug samples, driving-under-the-influence cases, overdose fatalities, and expanded NPS screening panels.

Key active research areas in 2026 include:

• Monoamine Transporter Activity & Selectivity 3-CEC acts as a potent blocker and substrate-type releaser at dopamine (DAT) and norepinephrine (NET) transporters, with weaker activity at the serotonin transporter (SERT). This catecholamine-dominant profile makes 3-CEC an excellent probe for studying DAT/NET-preferring stimulant mechanisms and comparing release vs reuptake inhibition ratios against ethcathinone, 3-MMC, 4-CMC, 3-CMC, α-PVP, and MDPV.
• Structure-Activity Relationship (SAR) Studies The meta-chloro substitution increases lipophilicity and steric bulk compared to unsubstituted ethcathinone, influencing potency, duration, selectivity, blood-brain barrier penetration, and metabolic fate. Researchers use 3-CEC to map how halogen position and size modulate transporter affinity, locomotor stimulation, and behavioral outcomes.
• Metabolite Identification & Forensic Toxicology 3-CEC undergoes extensive phase I metabolism (aromatic hydroxylation, N-dealkylation, β-keto reduction, and conjugation). Its primary metabolites are frequently detected in urine, blood, hair, and oral fluid in driving-under-the-influence, overdose, and postmortem cases. High-purity 3-CEC powder is essential for synthesizing reference standards, validating LC-QTOF-MS and GC-MS/MS methods, and confirming identity in routine NPS/stimulant screening panels.
• Behavioral Pharmacology & Locomotor Activity Rodent studies commonly employ 3-CEC dosage ranges of 0.3–10 mg/kg i.p. or s.c. to evaluate locomotor stimulation, stereotypy, conditioned place preference, self-administration liability, and cross-sensitization with cocaine, methamphetamine, or MDPV.
• Analytical Method Development & Validation 3-CEC is routinely included in expanded NPS/cathinone screening panels because it elutes close to ethcathinone, 3-MMC, 4-CMC, 3-CMC, and other ring-halogenated cathinones, requiring careful chromatographic separation and mass-spectral differentiation. It is also used to challenge the specificity of immunoassays and designer-drug screening tests.
• Pharmacokinetics & CYP450 Interaction Profiling The meta-chloro group slows certain metabolic pathways compared to unsubstituted cathinones, offering researchers a tool to study differential CYP enzyme involvement (CYP2D6, CYP2B6) and potential drug-drug interactions.

Typical Research Dosage Ranges (Reference Only – 2026)

3-CEC dosage varies significantly depending on the experimental model:

• Analytical calibration & reference standard preparation: 0.05–5 mg (standard curves, quality control)
• In-vitro transporter assays (DAT/NET/SERT): 0.1 nM – 10 μM (most active window: 30 nM – 3 μM)
• Rodent locomotor activity & behavioral pharmacology: 0.3–10 mg/kg i.p. or s.c. (dose-response curves common)
• High-dose neurochemical or toxicity modeling: 10–30 mg/kg (ethically restricted, IACUC-approved only)

Most published 3-CEC research centers on the 1–10 mg/kg range in vivo and 30 nM – 3 μM concentrations in cellular/transporter assays.

Safety, Handling & Regulatory Notes – 3-CEC Research Chemical

3-CEC is a potent monoamine-releasing agent and reuptake inhibitor and must be handled only under controlled laboratory conditions:

• Work exclusively in a certified Class II biological safety cabinet or fume hood
• Wear appropriate PPE: nitrile gloves, lab coat, safety goggles, and respiratory protection
• Prevent skin contact, inhalation, and aerosol generation
• Dispose of all waste as hazardous chemical material per institutional and local regulations
• Store in amber glass vials, sealed, at 2–8 °C, protected from light, heat, humidity, and air exposure

3-CEC side effects in research models are primarily related to excessive monoaminergic stimulation: hyperthermia, tachycardia, stereotyped behavior, increased seizure susceptibility, and potential neurotoxicity at high doses.

Legal status 2026: 3-CEC is controlled or monitored in many jurisdictions under analogue acts, temporary class drug orders, or specific NPS legislation. It is sold exclusively for legitimate scientific research, analytical reference, forensic calibration, and educational purposes. Buyers must independently confirm 3-CEC legal status in their jurisdiction prior to ordering.

Why Laboratories Consistently Choose Our 3-CEC Powder

• Third-party HPLC, GC-MS & NMR verified purity ≥98% – batch-specific COA included with every shipment
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, and method validation
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing risk
• Superior handling properties – fine, non-static powder with excellent flowability and solubility in common research solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, and research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance audits

We understand the critical role high-purity reference materials play in analytical chemistry, forensic toxicology, and neuropharmacology — every 3-CEC order is backed by that commitment.

Conclusion: Advance Cathinone & Stimulant Research with High-Purity 3-CEC Powder

In 2026, 3-CEC (3-Chloroethcathinone) remains a cornerstone compound for laboratories investigating synthetic cathinone metabolism, monoamine transporter dynamics, novel NPS emergence, and comparative SAR within the meta-halogenated cathinone family. Its high purity, consistent quality, reliable supply, and precise handling characteristics make 3-CEC powder an indispensable tool for rigorous forensic, toxicological, analytical, and pharmacological research.

Order your laboratory-grade 3-CEC today – strictly for scientific research, analytical, and forensic applications. Fast, discreet, tracked global delivery with full documentation and batch traceability.