3-MeO-PCE

Price range: $110.00 through $999.00

3-MeO-PCE Crystalline Powder
Research-grade 3-MeO-PCE (3-Methoxyeticyclidine) available in high-purity crystalline form. A member of the arylcyclohexylamine class, this compound is intended strictly for scientific and analytical research.

Key Features:

  • High-purity 3-MeO-PCE

  • Crystalline powder for precise dosing

  • Ideal for laboratory and analytical use

buy 3-MeO-PCE online — Advanced Arylcyclohexylamine Reference Standard for Analytical Research

🔬 Overview

3-Methoxyeticyclidine (3-MeO-PCE) is a dissociative arylcyclohexylamine compound that belongs to the eticyclidine (PCE) family. Structurally related to 3-MeO-PCP and O-PCE, it has become a central molecule of interest in contemporary forensic and neurochemical research.

Owing to its unique methoxy substitution at the 3-position, 3-MeO-PCE exhibits distinct analytical properties, making it a valuable reference standard for method validation, compound differentiation, and forensic profiling of arylcyclohexylamines.

At Global Chems Depot, we supply high-purity 3-MeO-PCE analytical-grade material intended solely for laboratory, forensic, and academic research — strictly not for human or veterinary use.


⚛️ Chemical Profile of arylcyclohexylamine reference

Property Description
Chemical Name 3-Methoxyeticyclidine
Synonyms 3-MeO-PCE, 3-Methoxy-N-ethylcyclohexylamine
Molecular Formula C₁₅H₂₃NO
Molecular Weight 233.35 g/mol
Compound Class Arylcyclohexylamine / Dissociative
Form Hydrochloride or freebase solid
Purity ≥ 99% analytical grade
CAS Number 1364933-53-6
Appearance White to off-white crystalline solid
Storage Keep in cool, dark, airtight conditions below –20°C

🧪 Scientific Context and Research Relevance of 3-MeO-PCE analytical standard

The arylcyclohexylamine family has been a major focus of pharmacological and analytical investigation since the synthesis of phencyclidine (PCP) and ketamine.
3-MeO-PCE serves as a structural analogue within this group, helping researchers explore structure–activity relationships (SAR), binding affinities, and metabolic pathways in both in vitro and ex vivo studies.

Because 3-MeO-PCE features both ether and ethyl substitutions, it exhibits physicochemical differences from its analogues that make it a valuable comparator in analytical detection and forensic differentiation.


🧬 Applications in Research and Analytical Science

1. Forensic Toxicology and Detection Studies

3-MeO-PCE is widely utilized in forensic laboratories for the identification and confirmation of dissociative analogues in seized samples.
Its unique mass spectral fragmentation pattern assists analysts in distinguishing it from compounds like 3-MeO-PCP, O-PCE, or MXPr.
Validated data from 3-MeO-PCE helps expand forensic reference databases (e.g., SWGDRUG, Cayman, NIST) used in criminal casework and toxicological screening.

2. Analytical Method Development

The compound is a key calibration standard for developing and validating chromatographic (HPLC, LC-MS, GC-MS) and spectroscopic analytical methods.
Its stable structure allows for precise quantification and method reproducibility, supporting the creation of multi-analyte panels in emerging NPS research.

3. Metabolic and Enzymatic Profiling

3-MeO-PCE has been the subject of studies exploring cytochrome P450-mediated metabolism and phase I/II transformations.
This research aids in understanding how structural modifications influence metabolic outcomes, providing insights into enzyme kinetics, hydroxylation, and demethylation pathways.

4. Comparative Structural Analysis

Researchers often use 3-MeO-PCE as a reference model in computational chemistry and molecular docking simulations.
These studies compare its binding orientation and receptor affinity against classical dissociatives to better understand its interaction mechanisms with NMDA receptor sites.


🧫 Analytical Characteristics of high purity 3-MeO-PCE research chemical

Technique Observations
Mass Spectrometry (MS) Prominent ions at m/z 233 (M⁺), 190, and 120. Useful in differentiating arylcyclohexylamines.
Infrared Spectroscopy (IR) Peaks at ~1,280 cm⁻¹ (C–O stretch), 1,610 cm⁻¹ (aromatic ring), and 2,900–2,950 cm⁻¹ (C–H stretch).
UV-Vis Spectroscopy Moderate absorption at 272–278 nm due to aromatic substitution.
NMR Spectroscopy (¹H, ¹³C) Signals confirming methoxy (–OCH₃) substitution and N-ethyl side chain.

These data form the foundation for reliable identification and quantification in laboratory analysis.


🌍 Forensic and Scientific Significance of arylcyclohexylamine reference

The rise of novel dissociative substances in global research contexts has underscored the need for accurate analytical references.
3-MeO-PCE occupies a unique niche among these compounds — its chemical stability, analytical clarity, and structural relevance make it a crucial reference molecule for both public and private research institutions.

It continues to be used in the development of forensic detection kits, analytical software validation, and comparative neurochemical mapping across universities and toxicology centers.


⚖️ Regulatory and Compliance Information of 3-MeO-PCE analytical standard

3-MeO-PCE may be controlled or restricted in some jurisdictions depending on national legislation related to arylcyclohexylamines.
Researchers and institutions are responsible for ensuring legal authorization prior to ordering or handling this compound.

All laboratory work must be conducted by qualified professionals in facilities equipped with proper chemical safety infrastructure, following regional compliance and reporting standards.


🧠 Safety and Handling Guidelines to buy 3-MeO-PCE online

  • Handle exclusively within certified laboratory environments.

  • Avoid direct contact and inhalation; use gloves, goggles, and fume extraction.

  • Store securely, away from light, heat, and moisture.

  • Dispose of all residues and containers via licensed hazardous waste channels.

  • Maintain documentation for all transfers and usage according to research safety guidelines.

Proper handling preserves compound stability and ensures full laboratory compliance.


🧩high purity 3-MeO-PCE research chemical Comparison with Related Compounds

Compound Key Structural Difference Primary Research Focus
3-MeO-PCE 3-Methoxy + N-Ethyl group Analytical validation, SAR research
3-MeO-PCP 3-Methoxy + N-Methyl group Forensic toxicology, comparison studies
O-PCE No methoxy group Pharmacological reference, metabolic studies
MXPr Cyclohexyl with propylamine Novel dissociative detection

This classification aids researchers in compound differentiation and forensic cross-comparison.


📘 Summary Table of 3-MeO-PCE laboratory use only

Compound Type: Arylcyclohexylamine / Dissociative
Form: Hydrochloride or freebase
Purity: ≥ 99% analytical standard
CAS Number: 1364933-53-6
Applications: Analytical method validation • Forensic research • NPS identification
Use Restriction: Research use only; not for human or animal consumption

⚠️ Important Notice

All information herein is provided strictly for scientific, analytical, and educational purposes.
3-MeO-PCE is not intended for human or veterinary use and may be subject to regulatory control.
This compound should only be handled by qualified researchers in licensed facilities under controlled conditions.

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