3F-PCP

buy 3F-PCP online: High-Purity 3-Fluoro-Phencyclidine Research Chemical (2026)

3F-PCP (3-Fluoro-Phencyclidine), commonly abbreviated as 3F-PCP research chemical or 3-Fluoro-PCP, is a synthetic arylcyclohexylamine dissociative closely related to phencyclidine (PCP), ketamine, and other PCP analogs. The addition of a fluorine atom at the meta (3) position of the phenyl ring modifies the compound’s lipophilicity, metabolic stability, NMDA receptor affinity, and overall pharmacological profile compared to the unsubstituted parent PCP.

Each batch of 3F-PCP powder is supplied as a fine, white to off-white crystalline material with ≥98% purity, independently verified by third-party high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), and proton nuclear magnetic resonance (¹H-NMR). The product is vacuum-sealed in tamper-evident, moisture-resistant foil pouches or amber glass vials to ensure long-term stability during storage and international shipping. Every order includes a current, batch-specific Certificate of Analysis (COA), lot traceability, and explicit “Research Use Only” labeling.

3F-PCP for sale is offered strictly for legitimate scientific research, analytical reference standard preparation, forensic method development/validation, toxicological profiling, and educational purposes — it is not intended, labeled, or sold for human or veterinary consumption, diagnostic use, therapeutic application, or any form of in-vivo experimentation outside approved research protocols.

Chemical & Physical Specifications – 3F-PCP Research Chemical

• Chemical Name: 1-(1-(3-Fluorophenyl)cyclohexyl)piperidine
• Common Synonyms: 3F-PCP, 3-Fluoro-PCP, 3-Fluoro-Phencyclidine
• CAS Registry Number: Not yet assigned (emerging research compound)
• Molecular Formula: C₁₇H₂₄FN
• Molecular Weight: 261.38 g/mol (freebase)
• Appearance: White to off-white fine crystalline powder
• Purity: ≥98.0% (third-party verified by HPLC, GC-MS, ¹H-NMR)
• Form: Vacuum-sealed, tamper-evident packaging
• Solubility: Highly soluble in ethanol, methanol, DMSO, chloroform; moderately soluble in acidified water
• Storage Conditions: Cool (2–8 °C), dry, dark, airtight container – protect from light, heat, humidity & air exposure
• Shelf Life: Typically 24–36 months under recommended conditions

Why Laboratories & Researchers Choose Our 3F-PCP Powder

• Independent third-party purity verification ≥98% – every batch ships with a detailed, current Certificate of Analysis showing HPLC chromatogram, GC-MS spectrum, and NMR confirmation
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, method validation, calibration curves, and inter-laboratory reproducibility
• Accurate net weight & no fillers – precise, reproducible dosing with no under- or over-dosing risk
• Superior handling properties – fine, low-static powder with excellent flowability and solubility in common analytical solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, government agencies & research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance audits

We understand the critical role high-purity reference materials play in analytical chemistry, forensic toxicology, neuropharmacology, and drug-monitoring programs — every 3F-PCP order is backed by that commitment.

Primary Research Applications of 3F-PCP (2026 Trends)

3F-PCP research chemical continues to attract significant interest in academic, forensic, and contract laboratories worldwide due to its structural position in the arylcyclohexylamine dissociative series and its continuing detections in illicit markets, polydrug samples, and postmortem toxicology cases.

Key active research areas in 2026 include:

• NMDA Receptor Antagonism & Channel Blocking 3F-PCP is a potent, non-competitive NMDA receptor antagonist with high affinity for the PCP binding site within the ion channel. It is used to study glutamate-mediated excitotoxicity, synaptic plasticity, long-term potentiation (LTP) disruption, and neuroprotection in ischemia/reperfusion models.
• Comparative Dissociative Pharmacology The meta-fluoro substitution increases lipophilicity and potentially prolongs duration of action compared to PCP while maintaining strong dissociative and psychotomimetic properties. Researchers compare 3F-PCP side-by-side with PCP, 3-MeO-PCP, 3-HO-PCP, ketamine, methoxetamine (MXE), and 2-FDCK to map fluorine effects on potency, selectivity, and therapeutic index.
• Metabolite Identification & Forensic Toxicology 3F-PCP undergoes extensive phase I metabolism (aromatic hydroxylation, N-dealkylation, piperidine ring oxidation). Its primary metabolites are frequently detected in urine, blood, hair, and oral fluid in driving-under-the-influence, overdose, and postmortem cases. High-purity 3F-PCP powder is essential for synthesizing reference standards, validating LC-QTOF-MS and GC-MS/MS methods, and confirming identity in routine NPS screening panels.
• Behavioral Pharmacology & Animal Models Rodent studies commonly employ 3F-PCP dosage ranges of 1–10 mg/kg i.p. or s.c. to evaluate locomotor activity, stereotypy, sensorimotor gating (PPI), conditioned place preference, self-administration liability, and cross-sensitization with ketamine or PCP.
• Analytical Method Development & Validation 3F-PCP is routinely included in expanded dissociative/NPS screening panels because it elutes close to other arylcyclohexylamines (3-MeO-PCP, 3-HO-PCP, ketamine) and requires careful chromatographic separation and mass-spectral differentiation. It is also used to challenge the specificity of immunoassays and designer-drug screening tests.
• Pharmacokinetics & CYP450 Interaction Profiling The 3-fluoro substitution slows certain metabolic pathways compared to unsubstituted PCP, offering researchers a tool to study differential CYP enzyme involvement (CYP2D6, CYP3A4) and potential drug-drug interactions.

Typical Research Dosage Ranges (Reference Only – 2026)

3F-PCP dosage varies significantly depending on the experimental model:

• Analytical calibration & reference standard preparation: 0.05–5 mg (standard curves, quality control)
• In-vitro NMDA receptor binding / channel assays: 0.1 nM – 10 μM (most active window: 10–300 nM)
• Rodent locomotor activity & behavioral pharmacology: 1–10 mg/kg i.p. or s.c. (dose-response curves common)
• High-dose neurochemical or toxicity modeling: 10–30 mg/kg (ethically restricted, IACUC-approved only)

Most published 3F-PCP research centers on the 1–10 mg/kg range in vivo and 10 nM – 300 nM concentrations in cellular/receptor assays, reflecting the compound’s high potency relative to ketamine.

Safety, Handling & Regulatory Notes – 3F-PCP Research Chemical

3F-PCP is a potent NMDA receptor antagonist and should be handled only under controlled laboratory conditions:

• Work exclusively in a certified Class II biological safety cabinet or fume hood
• Wear appropriate PPE: nitrile gloves, lab coat, safety goggles, and respiratory protection
• Prevent skin contact, inhalation, and aerosol generation
• Dispose of all waste as hazardous chemical material per institutional and local regulations
• Store in amber glass vials, sealed, at 2–8 °C, protected from light, heat, humidity, and air exposure

3F-PCP side effects in research models are primarily related to NMDA antagonism: dissociation, catalepsy, hyperlocomotion at low doses, stereotypy at higher doses, and potential neurotoxicity with chronic exposure.

Legal status 2026: 3F-PCP is controlled or monitored in many jurisdictions under analogue acts, temporary class drug orders, or specific NPS legislation. It is sold exclusively for legitimate scientific research, analytical reference, forensic calibration, and educational purposes. Buyers must independently confirm 3F-PCP legal status in their jurisdiction prior to ordering.

Why Laboratories Consistently Choose Our 3F-PCP Powder

• Third-party HPLC, GC-MS & NMR verified purity ≥98% – batch-specific COA included with every shipment
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, and method validation
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing risk
• Superior handling properties – fine, non-static powder with excellent flowability and solubility in common research solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, and research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance audits

We understand the critical role high-purity reference materials play in analytical chemistry, forensic toxicology, and neuropharmacology — every 3F-PCP order is backed by that commitment.

Conclusion: Advance Dissociative & NMDA Research with High-Purity 3F-PCP Powder

In 2026, 3F-PCP (3-Fluoro-Phencyclidine) remains a cornerstone compound for laboratories investigating NMDA receptor antagonism, dissociative pharmacology, novel NPS emergence, and comparative SAR within the arylcyclohexylamine family. Its high purity, consistent quality, reliable supply, and precise handling characteristics make 3F-PCP powder an indispensable tool for rigorous forensic, toxicological, analytical, and pharmacological research.

Order your laboratory-grade 3F-PCP today – strictly for scientific research, analytical, and forensic applications. Fast, discreet, tracked global delivery with full documentation and batch traceability.