5-Bromo-DMT FUMARATE

Buy 5-Bromo-DMT Fumarate online: High-Purity 5-Bromo-N,N-Dimethyltryptamine Fumarate Research Chemical

5-Bromo-DMT Fumarate (5-Bromo-N,N-dimethyltryptamine fumarate salt) is a halogenated tryptamine derivative that has become an increasingly important reference compound in contemporary serotonin receptor pharmacology, psychedelic analog research, neurochemical mapping, and forensic analytical chemistry. The strategic placement of a bromine atom at the 5-position of the indole ring significantly modifies the parent N,N-dimethyltryptamine (DMT) scaffold, altering receptor affinity profiles, metabolic stability, lipophilicity, and overall pharmacological behavior compared to unsubstituted DMT or other 5-substituted tryptamines such as 5-MeO-DMT and 5-HO-DMT (bufotenin).

Each batch of 5-Bromo-DMT Fumarate supplied by our laboratory is third-party verified to ≥99% purity by HPLC and ¹H-NMR, presented in the stable fumarate salt form to enhance aqueous solubility, shelf-life stability, and ease of handling in in-vitro and analytical workflows. The fumarate salt is the preferred form for most receptor binding, transporter assays, SAR investigations, and forensic reference standard applications.

We offer 5-Bromo-DMT for sale exclusively to verified research institutions, universities, contract research organizations (CROs), forensic toxicology laboratories, and licensed analytical facilities. Every order includes a current Certificate of Analysis (COA), batch traceability, tamper-evident packaging, and discreet, tracked global shipping to legally compliant jurisdictions.

Chemical & Physicochemical Specifications of 5-Bromo-DMT research chemical supplier

• Chemical Name: 5-Bromo-N,N-dimethyltryptamine fumarate
• IUPAC (freebase): 2-(5-bromo-1H-indol-3-yl)-N,N-dimethylethanamine
• CAS Number (freebase): 17274-14-3
• CAS Number (fumarate salt): Not separately assigned (commonly referenced to freebase)
• Molecular Formula (freebase): C₁₂H₁₅BrN₂
• Molecular Weight (freebase): 267.16 g/mol
• Molecular Formula (fumarate salt): C₁₂H₁₅BrN₂ · C₄H₄O₄
• Molecular Weight (fumarate salt): ≈ 383.24 g/mol
• Appearance: White to off-white crystalline powder
• Purity: ≥99.0% (HPLC area normalization, third-party verified)
• Form: Fine crystalline powder (fumarate salt)
• Solubility: Highly soluble in DMSO, ethanol, methanol; moderately soluble in water (acidified); slightly soluble in neutral water
• Storage Conditions: 2–8 °C, dry, dark, airtight container – protect from light, heat, humidity & air exposure
• Shelf Life: Typically 24–36 months under recommended conditions

Primary Research Applications of 5-Bromo-DMT Fumarate (2026)

5-Bromo-DMT research chemical continues to attract significant attention in the following key research domains:

• Serotonin Receptor Subtype Binding & Functional Assays 5-Bromo-DMT exhibits notable affinity at 5-HT1A, 5-HT2A, and 5-HT2C receptors, making it a valuable probe for studying partial agonism, biased signaling, and receptor desensitization patterns.
• Comparative Structure-Activity Relationship (SAR) Studies The bromine atom at the 5-position provides a unique electronic and steric perturbation compared to 5-MeO-DMT, 5-HO-DMT, and unsubstituted DMT, allowing direct evaluation of halogen effects on potency, efficacy, selectivity, and duration of action.
• Neurochemical Mapping & Monoamine Transporter Interactions While primarily serotonergic, 5-Bromo-DMT shows weaker but measurable activity at DAT and NET, offering researchers a tool to investigate mixed monoaminergic profiles within the tryptamine scaffold.
• Metabolite Identification & Forensic Toxicology Halogenated tryptamines are increasingly encountered in NPS markets and postmortem cases. High-purity 5-Bromo-DMT Fumarate serves as an essential reference standard for LC-QTOF-MS, GC-MS, and HPLC-DAD method development and confirmation.
• Psychedelic Analog Pharmacology & Behavioral Models Rodent head-twitch response (HTR), wet-dog shakes, locomotor activity, and drug discrimination paradigms frequently include 5-Bromo-DMT to compare hallucinogenic potential and receptor mediation with classic tryptamines.
• Analytical Method Validation & NPS Screening Panels 5-Bromo-DMT is routinely incorporated into expanded NPS libraries due to its chromatographic behavior, mass fragmentation patterns, and UV spectral characteristics that overlap with other tryptamine derivatives.

Typical Research Dosage & Concentration Ranges (Reference Only)

5-Bromo-DMT dosage varies significantly depending on the experimental model:

• In-vitro receptor binding & functional assays: 0.1 nM – 10 μM (most active range: 1–300 nM)
• Rodent behavioral pharmacology (HTR, locomotor): 0.3–10 mg/kg i.p. or s.c. (dose-response curves common)
• Analytical calibration & reference standards: 0.05–5 mg
• High-dose neurochemical / toxicity modeling: 10–30 mg/kg (ethically restricted, IACUC approval required)

Most published 5-Bromo-DMT research centers on the 1–10 mg/kg range in vivo and 1 nM – 1 μM concentrations in cellular/receptor assays.

Safety, Handling & Regulatory Notes – 5-Bromo-DMT Research Chemical

5-Bromo-DMT is a potent serotonergic compound and must be handled only in controlled laboratory environments:

• Work exclusively in a certified Class II BSC or fume hood
• Wear appropriate PPE: nitrile gloves, lab coat, safety goggles, respiratory protection
• Prevent skin contact, inhalation, and aerosol formation
• Dispose of all waste as hazardous chemical material per institutional & local regulations
• Store in amber glass vials, sealed, at 2–8 °C, protected from light & humidity

5-Bromo-DMT side effects in research models include hyperthermia, tachycardia, head-twitch response, wet-dog shakes, and potential serotonin syndrome-like symptoms at high doses.

Legal status 2026: 5-Bromo-DMT is controlled or monitored in many jurisdictions under analogue acts, temporary class drug orders, or specific NPS legislation. It is sold exclusively for legitimate scientific research, analytical reference, forensic calibration, and educational purposes. Buyers must confirm local laws before ordering.

Why Laboratories Choose Our 5-Bromo-DMT Fumarate

• Third-party HPLC & NMR verified purity ≥99% – batch-specific COA included
• Stable fumarate salt – improved solubility, shelf life & handling vs freebase
• Consistent batch-to-batch quality – ideal for longitudinal & multi-site studies
• Secure, tamper-evident packaging – moisture-resistant & discreet
• Fast, tracked global shipping – chain-of-custody documentation available
• Bulk & institutional pricing – tailored rates for universities, CROs & forensic labs

We understand the critical role reference materials play in analytical and pharmacological research – every 5-Bromo-DMT order is backed by that commitment.

Conclusion: Advance Serotonin Receptor & Tryptamine Analog Research with High-Purity 5-Bromo-DMT Fumarate

In 2026, 5-Bromo-DMT Fumarate continues to serve as a cornerstone reference compound for laboratories investigating 5-HT1A/5-HT2A/5-HT2C receptor pharmacology, benzofuran vs indole SAR, entactogen-like monoamine release profiles, and forensic detection of halogenated tryptamine NPS. Its high purity, stable fumarate salt form, and reliable supply make 5-Bromo-DMT an indispensable tool for rigorous serotoninergic, neurochemical, and analytical research.

Purchase 5-Bromo-DMT online today – strictly for scientific research, forensic, and analytical applications. Fast, discreet, tracked global delivery with full documentation.