5-Chloro-DMT Fumarate

buy 5-Chloro-DMT Fumarate online: Premium Halogenated Tryptamine Research Chemical in 2026

In the cutting-edge realm of research chemicals, 5-Chloro-DMT Fumarate stands as a fascinating halogenated tryptamine for in-depth laboratory investigations. Known scientifically as 5-Ch-DMT Fumarate or 5-chloro-N,N-dimethyltryptamine fumarate, this compound is a chlorinated derivative of the classic N,N-dimethyltryptamine (DMT). Researchers searching “buy 5-Chloro-DMT Fumarate online” or “5-Cl-DMT Fumarate for sale” will find our high-purity product ideal for exploring serotonergic systems and psychedelic pharmacology.

As 2026 approaches, interest in tryptamine research chemicals like 5-Chloro-DMT Fumarate surges among neuroscientists and pharmacologists. Naturally occurring in marine sponges such as Smenospongia aurea and Verongula rigida, this compound offers unique insights into 5-HT2A and 5-HT1A receptor interactions. The fumarate salt enhances stability and solubility, making it superior for precise experiments. Sold strictly for research purposes only—not for human consumption—our page targets high-volume searches like “high purity 5-Chloro-DMT Fumarate” and “halogenated tryptamines 2026” with detailed, evidence-based information.

What Is 5-Chloro-DMT Fumarate? Essential Chemical Profile

5-Chloro-DMT Fumarate is a substituted tryptamine with a chlorine atom at the 5-position of the indole ring. Its IUPAC name is 2-(5-chloro-1H-indol-3-yl)-N,N-dimethylethan-1-amine fumarate, with a base molecular formula of C12H15ClN2 and weight of 222.72 g/mol. The fumarate salt form appears as a white to off-white crystalline powder, improving handling over freebase versions.

This compound shares structural similarities with DMT, 5-bromo-DMT, and 5-fluoro-DMT, but the chlorine substitution alters receptor affinity and efficacy. Researchers querying “5-Chloro-DMT properties” note its biased agonism at 5-HT2A receptors, with higher β-arrestin2 recruitment compared to G-protein signaling. Naturally isolated from sea sponges alongside 5,6-dibromo-DMT, it represents an intriguing bridge between marine alkaloids and synthetic analogs.

In lab settings, 5-Chloro-DMT Fumarate’s stability allows for reliable HPLC, NMR, and binding assays. High-search terms like “5-Cl-DMT research chemical” underscore its role in structure-activity relationship (SAR) studies within the tryptamine class.

Research Benefits and Applications of 5-Chloro-DMT Fumarate

Purchasing 5-Chloro-DMT Fumarate powder opens doors to advanced serotonergic research. Key advantages include:

1. Serotonin Receptor Insights: Acts as a partial agonist at 5-HT2A (with lower calcium mobilization than DMT) and 5-HT1A, inducing head-twitch response in rodents—a proxy for psychedelic effects.
2. Behavioral Models: Studies suggest hypolocomotion, hypothermia, and potential sedative/antidepressant-like activity in forced swim tests.
3. Comparative Pharmacology: Ideal for contrasting halogenated tryptamines (e.g., vs. 5-bromo-DMT or 5-fluoro-DMT) in biased signaling pathways.
4. Analytical Precision: Fumarate form ensures excellent solubility in polar solvents, facilitating accurate dosing in vitro.
5. Neurochemistry Exploration: Supports investigations into neurotransmitter release and receptor desensitization.

Animal models highlight intermediate potency among halogenated derivatives, making it valuable for “tryptamine serotonin research 2026.” Unlike more potent psychedelics, its profile may reveal nuanced mood regulation mechanisms.

Laboratory Handling and Usage Guidelines for 5-Chloro-DMT Fumarate

Safe, effective use of 5-Chloro-DMT Fumarate requires strict protocols. Research concentrations typically span micrograms to milligrams, scaled by assay type.

Recommended Practices:

• Solubility: Readily dissolves in water, ethanol, or saline—prepare fresh solutions.
• Storage: Store in a cool, dry, dark place in airtight containers; stable for years.
• Safety Measures: Wear PPE (gloves, mask, goggles); potential respiratory/ocular irritant. Use fume hoods.
• Analytical Methods: Combine with GC-MS or LC-MS for purity verification.

For “5-Chloro-DMT Fumarate research protocols,” focus on receptor binding or behavioral assays. Always include controls and document variables for reproducibility.

Research Observations and Safety Considerations

In studies, 5-Chloro-DMT elicits milder psychedelic-like effects compared to DMT, with reported vaporized doses of 20-50 mg producing subtle activity. Rodent data shows hypolocomotion and hypothermia via 5-HT1A.

Potential irritations include respiratory or eye effects during handling. As an emerging compound, comprehensive toxicity data is limited—adhere to lab-only use. High-volume queries like “5-Cl-DMT safety” stress ethical guidelines and proper ventilation.

Legal Status of 5-Chloro-DMT Fumarate in 2026

Legal status varies: Often unscheduled in many jurisdictions for research sales, but may fall under analog acts (e.g., US Federal Analogue Act if misused). Restricted in some countries (e.g., certain territories limit shipping).

Our 5-Chloro-DMT Fumarate is labeled for research only, with compliance checks. Verify local regulations for “5-Chloro-DMT legal status 2026.”

Why Select Our 5-Chloro-DMT Fumarate Powder?

For “buy research chemicals online” searches, we excel with:

• 98%+ Purity: Third-party tested, COAs provided.
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Related Compounds and Alternatives

Explore analogs like:

• 5-Bromo-DMT Fumarate
• 5-Fluoro-DMT
• Standard DMT precursors

Supporting “halogenated tryptamine analogs” research.

FAQs on 5-Chloro-DMT Fumarate

• Where to buy 5-Chloro-DMT Fumarate? Securely from us—research exclusive.
• Purity level? 98%+, verified.
• Natural occurrence? Yes, in marine sponges.
• Suitable for serotonin studies? Excellent for 5-HT2A/1A.

Conclusion: Pioneer Tryptamine Research with 5-Chloro-DMT Fumarate

In 2026, 5-Chloro-DMT Fumarate powder drives innovation in psychedelic and neurochemical research. Targeting “buy 5-Cl-DMT Fumarate 2026” or halogenated derivatives, our product guarantees purity and reliability. Advance your lab work today—strictly for scientific purposes