5-DBFPV

Buy 5-DBFPV online: High-Purity 5-Dihydrobenzofuranpyrovalerone Research Chemical

5-DBFPV (5-Dihydrobenzofuranpyrovalerone), also commonly referred to as 5-DBFPV research chemical, is a synthetic cathinone derivative belonging to the pyrrolidine-substituted cathinone class. It is structurally related to MDPV (methylenedioxypyrovalerone), α-PVP (α-pyrrolidinopentiophenone), and other pyrovalerone analogs, but features a distinctive 2,3-dihydrobenzofuran ring system instead of the typical phenyl or 3,4-methylenedioxyphenyl ring. This modification significantly influences its lipophilicity, metabolic stability, monoamine transporter affinity, and overall pharmacological profile, making 5-DBFPV a compound of growing interest in neuropharmacology, forensic toxicology, analytical method development, and structure-activity relationship (SAR) studies in 2026.

Each batch of 5-DBFPV powder is supplied as a fine, off-white to light beige crystalline material with ≥98% purity, confirmed by third-party high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), and nuclear magnetic resonance (NMR) analysis. The product is vacuum-sealed in tamper-evident, moisture-resistant packaging to ensure long-term stability and integrity during storage and international shipping.

5-DBFPV for sale is intended strictly for legitimate scientific research, analytical reference, forensic calibration, and educational purposes — not for human or veterinary consumption, diagnostic, therapeutic, or recreational use.

Chemical & Physical Specifications by 5-DBFPV research chemical supplier

• Chemical Name: 1-(2,3-Dihydrobenzofuran-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one
• Common Synonyms: 5-DBFPV, 5-Dihydrobenzofuranpyrovalerone
• CAS Registry Number: Not yet assigned (emerging research compound)
• Molecular Formula: C₁₇H₂₅NO₂
• Molecular Weight: 275.39 g/mol
• Appearance: White to off-white fine crystalline powder
• Purity: ≥98.0% (third-party verified by HPLC, GC-MS, and ¹H-NMR)
• Form: Vacuum-sealed, tamper-evident packaging
• Solubility: Highly soluble in ethanol, methanol, DMSO, chloroform; moderately soluble in acidified water
• Storage Conditions: Cool (2–8 °C), dry, dark, airtight container – protect from light, heat, humidity, and air exposure
• Shelf Life: Typically 24–36 months under recommended conditions

Why Laboratories & Researchers Choose Our 5-DBFPV Powder

• Independent third-party purity verification – every batch ships with a current, detailed Certificate of Analysis (COA) showing HPLC chromatogram, GC-MS spectrum, and NMR confirmation
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, method validation, and reproducibility
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing
• Superior handling properties – fine, non-static powder with excellent flowability and solubility in common research solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, and research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance

We understand the critical importance of reliable, high-purity reference materials in analytical chemistry, forensic toxicology, and neuropharmacology — every 5-DBFPV order is backed by that commitment.

Primary Research Applications of 5-DBFPV research chemical (2026 Trends)

5-DBFPV research chemical continues to attract significant attention in academic, forensic, and contract laboratories worldwide due to its structural uniqueness and pharmacological profile. Key active research areas in 2026 include:

• Monoamine Transporter Activity 5-DBFPV research chemical is a potent inhibitor and releaser at dopamine (DAT) and norepinephrine (NET) transporters, with weaker activity at the serotonin transporter (SERT). This makes it a valuable probe for studying catecholamine-dominant stimulant mechanisms, comparing release vs reuptake inhibition ratios, and evaluating transporter subtype selectivity.
• Structure-Activity Relationship (SAR) Studies The 2,3-dihydrobenzofuran core differentiates 5-DBFPV from classical cathinones (phenyl or methylenedioxyphenyl scaffolds). Researchers use 5-DBFPV to investigate how ring fusion, fluorine absence, and pyrrolidine substitution influence potency, duration, selectivity, and metabolic fate compared to MDPV, α-PVP, 3-MMC, 4F-MPH, and other analogs.
• Receptor Affinity & Signal Transduction Binding and functional assays at DAT, NET, SERT, TAAR1, and trace amine-associated receptors help map downstream signaling pathways, β-arrestin recruitment, and potential biased agonism.
• Metabolite Identification & Forensic Toxicology 5-DBFPV and its major metabolites (O-demethylated, N-dealkylated, hydroxylated, and conjugated forms) are increasingly detected in postmortem blood, urine, and hair. High-purity reference material is essential for LC-QTOF-MS, GC-MS/MS, and HPLC-DAD method development, validation, and confirmation in forensic casework.
• Behavioral Pharmacology & Locomotor Activity Rodent studies frequently employ 5-DBFPV dosage ranges of 0.3–10 mg/kg i.p. or s.c. to evaluate locomotor stimulation, stereotypy, conditioned place preference, self-administration, and cross-sensitization with cocaine or methamphetamine.
• Analytical Method Development 5-DBFPV is routinely included in expanded NPS screening panels because it elutes close to other cathinones and benzofurans, requiring careful chromatographic separation and mass spectral differentiation.

Typical Research Dosage Ranges (Reference Only – 2026)

5-DBFPV dosage varies significantly depending on the experimental model:

• Analytical calibration & reference standard preparation: 0.05–5 mg (standard curves, quality control)
• In-vitro transporter assays (DAT/NET/SERT): 0.1 nM – 10 μM (most active window: 30 nM – 3 μM)
• Rodent locomotor activity & behavioral pharmacology: 0.3–10 mg/kg i.p. or s.c. (dose-response curves common)
• High-dose neurochemical or toxicity modeling: 10–30 mg/kg (ethically restricted, IACUC-approved only)

Most published 5-DBFPV research centers on the 1–10 mg/kg range in vivo and 30 nM – 3 μM concentrations in cellular/transporter assays, reflecting the compound’s high potency relative to non-fluorinated cathinones.

Safety, Handling & Regulatory Notes – 5-DBFPV Research Chemical

5-DBFPV is a potent monoamine-releasing agent and reuptake inhibitor and must be handled only under controlled laboratory conditions:

• Work exclusively in a certified Class II biological safety cabinet or fume hood
• Wear appropriate PPE: nitrile gloves, lab coat, safety goggles, and respiratory protection
• Prevent skin contact, inhalation, and aerosol generation
• Dispose of all waste as hazardous chemical material per institutional and local regulations
• Store in amber glass vials, sealed, at 2–8 °C, protected from light, heat, humidity, and air exposure

5-DBFPV side effects in research models are primarily related to excessive monoaminergic stimulation: hyperthermia, tachycardia, stereotyped behavior, increased seizure susceptibility, and potential neurotoxicity at high doses.

Legal status 2026: 5-DBFPV is controlled or monitored in many jurisdictions under analogue acts, temporary class drug orders, or specific NPS legislation. It is sold exclusively for legitimate scientific research, analytical reference, forensic calibration, and educational purposes. Buyers must independently confirm 5-DBFPV legal status in their jurisdiction prior to ordering.

Why Laboratories Consistently Choose Our 5-DBFPV research chemical

• Third-party HPLC, GC-MS & NMR verified purity ≥98% – batch-specific COA included with every shipment
• Consistent batch-to-batch quality – essential for longitudinal studies, multi-site collaborations, and method validation
• Accurate net weight & no fillers – precise, reproducible dosing with zero under- or over-dosing
• Superior handling properties – fine, non-static powder with excellent flowability and solubility in common research solvents
• Secure, discreet, tracked global shipping – plain packaging, chain-of-custody documentation available upon request
• Competitive bulk & institutional pricing – tailored volume discounts for universities, contract research organizations (CROs), forensic laboratories, and research consortia
• Research-use-only labeling & compliance support – clear documentation to support legitimate scientific intent and regulatory compliance

We understand the critical role high-purity reference materials play in analytical chemistry, forensic toxicology, and neuropharmacology — Purchase 5-DBFPV powder every order is backed by that commitment.

Conclusion: Advance Cathinone & Stimulant Research with High-Purity 5-DBFPV research chemical

In 2026, 5-DBFPV (5-Dihydrobenzofuranpyrovalerone) remains a cornerstone compound for laboratories investigating synthetic cathinone metabolism, monoamine transporter dynamics, novel NPS emergence, and comparative SAR within the pyrrolidine-substituted cathinone family. Its high purity, consistent quality, reliable supply, and precise handling characteristics make 5-DBFPV powder an indispensable tool for rigorous forensic, toxicological, analytical, and pharmacological research.

Purchase 5-DBFPV powder today – strictly for scientific research, analytical, and forensic applications. Fast, discreet, tracked global delivery with full documentation and batch traceability.